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Additional stroke symptoms can include: Sudden face or limb weakness Sudden confusion or visual disturbances Difficulty speaking clearly Otherwise unexplained headaches Lack of coordination or dizziness In addition to severe pain in the left arm, heart attack symptoms include: Chest or back pain or discomfort Neck or jaw pain or discomfort Sudden shortness of breath Nausea or lightheadedness Unexplained cold sweats If you experience any of these symptoms combined with arm pain, seek immediate medical attention

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Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis